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In vitro experiments have shown that GPX4 or FSP1 overexpression protects CD8 + T cells from ferroptosis, while application of GPX4 inhibitor significantly increases the sensitivity of T cells to ferroptosis

The biologic potential of various categories of melanocytomas needs to be determined by careful clinical observational studies in order to guide optimal patient management

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6 Conclusion Finally, we integrate the main points from earlier sections to highlight ferroptosis as a promising research and therapeutic direction in OA (201)