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Although gout can be considered an acute consequence of periods of hyperuricemia and is easily recognizable by the associated severe joint pain, particularly in the large toe joints, there are many metabolic disturbances that result from chronic hyperuricemia that are far more problematic from the perspective of morbidity and mortality

When you take GLP-1 medications, they mimic the GLP-1 hormone that is released in the gastrointestinal tract when you eat

That extended residence time creates a perfect environment for bacterial fermentation

18,19 The multifactorial nature of GI diseases, including altered motility, microbial dysbiosis, and visceral hypersensitivity, makes single-target therapies insufficient

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