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to inhibit VEGF-induced endothelial cell proliferation and/or migration or angiogenesis, without significantly inhibiting VEGFRl stimulation of osteoclasts or chondroclasts

In the CFA-induced chronic inflammatory pain model, mice with CFA-induced inflammation presented prolonged heat hyperalgesia following intraplantar vehicle administration

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The model, beginning in 2026 for Medicaid and 2027 for Medicare, is voluntary for drug manufacturers, state Medicaid programs, and Medicare Part D plans

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