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Xia Y, Kelton CM, Guo JJ, Bian B, Heaton PC (2015) Treatment of obesity: pharmacotherapy trends in the United States from 1999 to 2010

Meanwhile, NF1 is significantly co-mutated with KIT in 32% of MMs, whereas the co-occurrence level in CM is merely 4% (99), which indicates that the MAPK cascade is upregulated in MM not only by the single protein in the cytoplasm but also by the assistance of C-KIT receptor on the cell membrane