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The heterogeneity and differential expression of protein kinase C in nervous tissues

It has been hard to understand how it contributes to the development of HD either from post-mortem human brain analysis or from rodent models carrying mHTT, as the latter affects many signalling pathways

Aglietti RA, Estevez A, Gupta A et al (2016) GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

The 1 receptor class are coupled to G q -type G-proteins that activate PLC resulting in increases in IP 3 and DAG release from membrane PIP 2

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