Its a moment to take a breath
Indeed, besides a familial component in insulin resistance, as in general population, patients with PWS have fairly low fasting insulin concentrations and a lower incidence of insulin resistance compared to that expected considering the body mass index (BMI), probably due to a greater distribution of adipose tissue in the subcutaneous than in visceral site [15, 29, 30]
Yes, GLP-1 medications should be discontinued before planned conception: at least 2 months before for semaglutide, at least 1 month for tirzepatide, and when pregnancy is recognized for other agents
That premature decision resulted in unnecessary patient angst and interruptions of therapy when pharmacies could not access the FDA-approved drugs for those patients
Branded Ozempic versus compounded semaglutide The two routes share a compound class but differ in sourcing and oversight