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Thiamine and its pharmacological forms, as a primary or adjunctive therapy, have been shown to improve symptoms such as nausea, constipation, dysphagia and intestinal dysmotility, in both humans and animals

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Always patch-test before increasing the dosage or frequency to prevent irritation

The regulatory environment for actually collecting data and running trials on them

It can be treated in the long run by a class of meds that may cause some immune system complications . Yes doc, I am familiar with the complications