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(2003) showed that KPV suppressed inflammatory cytokine production even in the presence of melanocortin receptor antagonists, confirming receptor-independent activity

Abnormalities in mitochondrial structure and defects in mitophagy have been identified in the neurons of patients with sporadic ALS (Rodriguez et al., 2012

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doi: 10.1152/ajpendo.00270.2002

Brain Res 1764:147468 Singh N, Saha L, Kumari P et al (2019) Effect of dimethyl fumarate on neuroinflammation and apoptosis in pentylenetetrazol kindling model in rats [J]