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Use with Medications Known to Cause Hypoglycemia Sitagliptin As is typical with other antihyperglycemic agents used in combination with a sulfonylurea, when sitagliptin was used in combination with metformin and a sulfonylurea, a medication known to cause hypoglycemia, the incidence of hypoglycemia was increased over that of placebo in combination with metformin and a sulfonylurea [see Adverse Reactions]

Clinical observations suggest it may improve range of motion and reduce pain over time, though human evidence is still limited and a medical evaluation is important

When you take this medication, it signals your brain that you are full, which helps reduce overall calorie intake

doi: 10.1039/D1RA03640H 472 ChenBHHsiehCHTsaiSYWangCYWangCC

Body composition / lean mass Studied as a GH secretagogue for effects on lean mass and body composition