Meals that would have left you wanting more now leave you feeling comfortably full, sometimes even uncomfortably so if you attempt to eat your usual portion sizes
[7] That preclinical promise carried the compound into a human Phase II program for postoperative ileus but the randomized, placebo-controlled trial in bowel-resection patients did not meet its primary efficacy endpoint, and clinical development was subsequently discontinued
Qin C, Yang S, Chu YH, Zhang H, Pang XW, Chen L, et al
Most protocols recommend a 24 week break after a cycle to reassess progress and prevent diminishing returns
The STEP clinical trials have demonstrated average weight reductions of 10-15% of body weight over 68 weeks when combined with lifestyle modifications