Yellow arrowheads, LAG-1 accumulation in the sheath cells, red arrowheads, WAPL-1 accumulation in sheath cells
Gupta emphasizes that weight regain is common after discontinuing the medication, making it clear that GLP-1s should not be seen as a quick fix. These medications are a valuable tool, but they work best when combined with other strategies, he notes
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Some strategies that help: Start every meal with your protein source before eating anything else Use protein shakes or protein supplements to hit targets on days when solid food is unappealing Choose protein-dense foods: Greek yogurt, cottage cheese, eggs, lean meats, fish Spread protein across all meals rather than trying to get it all in one sitting The tirzepatide eating guide provides a full breakdown of optimal food choices, and the diet plan offers structured daily meal examples specifically designed for people on GLP-1 medications
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