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Non-solubilized folic acid in dry materials is not sensitive to irradiation treatment, while it is easily degraded in aqueous solutions 348,349

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According to the most recent WHO report, 2023 Antibacterial agents in clinical and preclinical development: an overview and analysis (data collected up to the end of 2023), there are nearly a hundred new chemical entities in the trials, out of which 26 are labeled as innovative depending on if they meet one or more of the four WHO criteria (new chemical class, new target, new mode of action or absence of cross-resistance) [59]

doi: 10.1016/j.resmic.2013.03.009 135 JametA.JoussetA