tirzepatide journal Tirzepatide: A novel, first-in-class, dual GIP/GLP-1 receptor agonist Tirzepatide Once Weekly in Children

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Studied in laboratory research on tissue repair and the formation of new blood vessels

Key findings at the highest dose (12mg weekly): Up to 24% mean body weight reduction over 48 weeks Significant reductions in fasting glucose and insulin resistance markers Meaningful reductions in liver fat content, relevant for participants with metabolic-associated fatty liver disease Once-weekly subcutaneous dosing was generally well-tolerated For context, semaglutide at its approved dose achieves approximately 1517% body weight reduction over 68 weeks

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