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Weight loss during pregnancy is not recommended, and animal studies have shown potential foetal risks

The SMD of 15.82 represents a standardised effect size rather than a direct hair count

The medication is administered once every seven days, with dosing typically initiated at 2.5 mg and gradually titrated upward in 2.5 mg increments no more frequently than every 4 weeks, based on therapeutic response and tolerability

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Research indicates that GLP-1 receptors are highly concentrated in the mesolimbic reward system the brains hub for dopamine and impulsivity ( PMC , 2025)