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Emerging techniques such as basophil activation tests (BAT) and component-resolved diagnostics (CRD) show promise in improving diagnostic accuracy without the need for confirmatory OFC [66,67,68,69]

At one year, orforglipron met the primary and all key secondary endpoints compared to placebo, delivering superior weight maintenance as an adjunct to a healthy diet and physical activity, using the efficacy estimand and modified treatment-regimen estimand

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The experimental diets incorporated fish meal as the protein source, corn starch as the carbohydrate source, and a combination of fish oil and soybean oil as the fat sources

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