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An analysis of the mechanism reveals that the nanoparticles facilitate the oxidation of GSH into GSSG, leading to disruptions in redox balance and the antioxidant defense system and therefore accumulation of ROS and lipid peroxides

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2 Introduction Parkinson's disease is a degenerative disease of the central nervous system resulting from depletion of dopamine-producing cells in a region of the brain called the substantia nigra