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Overexpression of pro-inflammatory IL-8, along ide IL-6 and TNF-, has been associated with inflammatory processes in the digestive system, particularly in the intestines, inducing inflammatory bowel disease (IBD) [139]

This is why I said losing weight with a GLP-1 agonist is like taking two steps backward: When you drop your muscle mass by 50%, you are losing a huge chunk of daily caloric burn