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Eur J Clin Pharmacol 43:667669

This is important because it indicates that any increase in systemic GLP-1 levels (for example through medication) could potentially influence the amount that reaches the joint. Tue Wenzel Kragstrup, MD, PhD The next step (in this research) is to find out whether GLP-1-based drugs reach the joints in high enough concentrations to have biological effects there, Kragstrup continued

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with one of the randomized, controlled trials contributing to its FDA approval demonstrating up to 8.2% weight loss