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This inhibition prevents the release and nuclear translocation of the NF-B p65 subunit, thereby attenuating downstream inflammatory signaling (256, 257)

[2, 4, 5] How our environment influences obesity If our genetics haven't changed since the 1900s, is the environment to blame for the rise in obesity

Interestingly, ZIP13-deficient mice show increased biogenesis of beige adipocytes due to accelerated differentiation of preadipocytes into beige cells, suggesting that ZIP13 physiologically acts as a negative regulator of adipocyte browning

10.1016/S0014-2999(99)00105-3 213 PandeyS