"It's a bunch of great things that come along with this." Meghan Trainor Meghan Trainor's dramatic weight loss after the birth of her second child has been well-documented, and she's not shied away from sharing how she did it

FDA-approved semaglutide brands and indications Brand Ozempic (injectable) Approval date December 2017 Indication Type 2 diabetes glycemic control Brand Ozempic (injectable) Approval date January 2020 Indication Cardiovascular risk reduction in T2D Brand Rybelsus (oral tablet) Approval date September 2019 Indication Type 2 diabetes (first oral GLP-1) Brand Wegovy (injectable) Approval date June 2021 Indication Chronic weight management (BMI 30 or 27 with comorbidity) Brand Wegovy (injectable) Approval date March 2024 Indication Cardiovascular risk reduction in adults with obesity and CVD Brand Wegovy (injectable) Approval date August 2025 Indication Non-cirrhotic MASH with F2-F3 fibrosis (ESSENCE) Brand Wegovy oral 25 mg pill Approval date December 2025 Indication Chronic weight management (OASIS 4 basis) Brand Ozempic (injectable) Approval date February 2026 Indication CKD progression in T2D (FLOW basis) Research-grade lyophilized semaglutide from supplier sources is not an FDA-approved drug product and is for research use only

This can create a physical sensation of being "wired" or anxious, especially when trying to fall asleep
The SUSTAIN-6 cardiovascular outcome trial, with approximately 2.1 years of follow-up, and the SELECT trial, with over 3 years of follow-up, have not identified safety signals for thyroid malignancy
The psychological impact of weight loss is highly individual and influenced by personal history, relationship dynamics, and mental health status