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Another study evaluated the nephrotoxic effect of DZN in rats and found that it significantly increased renal lipid peroxidation, decreased antioxidant enzyme activities, and reduced glutathione levels, indicating its ROS-generation potential [6]

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Vandenbeuch A, Anderson CB, Parnes J, Enjyoji K, Robson SC, Finger TE, Kinnamon SC

Additionally, there is an immediate demand for the creation and application of reliable, standardized biomarkers of aging to assess therapeutic effectiveness not through clinical indicators of metabolic regulation, but through biological aging