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Its essential to remember that while B12 can support weight loss and energy levels, optimal results often come from consistent treatment combined with a balanced lifestyle

however, research has not shown an increased prevalence of a deficiency in people using these medications

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Another significant metformin side effect: vitamin B12 deficiency

View on PubMed Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model Demonstrated AOD9604 intra-articular injection reduced cartilage degradation and inflammatory markers in a collagenase-induced knee osteoarthritis rabbit model, with the combination of AOD9604 and hyaluronic acid showing additive chondroprotective effects (Ann Clin Lab Sci, 2015)