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The review provides an introduction to the reproductive toxicity of SSRIs from the aspects of male and female germ cell genesis, embryonic development, reproductive system maturation, and environmental contamination, and it briefly describes the potential mechanisms underlying SSRI-induced reproductive toxicity

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Pharmacology [edit] Metabolism and half-life [edit] Tesofensine has a long half-life of about 9 days (220 h) [4] "and is mainly metabolized by cytochrome P4503A4 (CYP3A4) to its desalkyl metabolite M1" NS2360

Hinson JA, Roberts DW, James LP

3,16,205 The combination of intrauterine insemination with ovulation-inducing drugs also may be used in the setting of male infertility due to low sperm counts