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If the total melatonin load in these species was derived exclusively from the pineal gland, they would be devoid of all melatonin for a significant portion of each year

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Rapid weight loss can cause an aged appearance mostly because patients lose the fat pads characteristic of youthful facial contours, says Jessica Weiser, MD, a board-certified dermatologist and founder of Weiser SkinMD with locations in NYC and Aspen