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A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis

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It coordinates endogenous and exogenous resistance by directly acting on and participating in the enzymatic reactions of certain antioxidant enzymes

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GSH is an antioxidant that regulates oxidative stress, drug detoxification and post-translational modifications 2

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doi: 10.1096/fasebj.8.15.8001745

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