Risk factors that should prompt consideration of B12 deficiency include advancing age (reduced stomach acid production), strict vegan or vegetarian diets, pernicious anaemia, gastrointestinal surgery (particularly gastric bypass or ileal resection), long-term use of certain medications (metformin, proton pump inhibitors, H2-receptor antagonists), nitrous oxide exposure (including recreational use), and conditions affecting the gut such as Crohn's disease or coeliac disease
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Check thyroid function if using longterm, as subclinical hypothyroidism can blunt GH response [5]
At the gene expression level, ZEB1, SIRT1, and CD16 mRNA levels were increased following 5MQ treatment, while TWIST and SERPIN1 mRNA levels were reduced
Regarding oocyte and embryo outcomes, the number of mature oocytes was significantly higher in the High and Average groups than in the Low group (Average vs
