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In his opinion, it has highlighted the importance of individualised care and close monitoring for B12 replacement therapy

The results of studies with CSF levels of iron and copper are controversial (Table 3), but a recent meta-analysis showed similar values in PD patients to controls (Mariani et al., 2013), thus suggesting that these metals are not useful as markers of PD

Summary Data from animal models of hypertension support they have increased gut permeability

2015 Jun;48(6):e11-26

They also suggest the need for additional studies to examine the mechanisms by which TGF and GHK each reverse the gene-expression signature of emphysematous destruction and the effects of this reversal on disease progression