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Excessively rapid reductions in blood pressure can cause uncontrollable hypotension and hypoperfusion, which has historically resulted in permanent cortical blindness (Morton and Hickey-Dwyer, 1992), myocardial infarction (Messerli and Eslava, 2008), and devastating ischemic strokes (Schwartz et al, 1990

for comparison, the results relative to the interactions between p53/p28 and p53 DBD/p28 were also reported

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BMJ Open 2019;9:e028007

Circulation 2000