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AOD-9604 AOD-9604 is a synthetic peptide fragment of human growth hormone (residues 176-191) with a tyrosine substitution at the N-terminal position

Contributes to normal nerve function

Microglia activation stimulates the secretion of several proinflammatory molecules like tumor necrosis factor- (TNF-), interleukin (IL)-1, nitric oxide, vascular endothelial growth factor-B, or complement factor Cq1 that can induce a modification of the astrocyte phenotype towards A1 reactive (Liddelow et al., 2017)

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Wegovy is the brand name for semaglutide at the 2.4 mg dose, made by Novo Nordisk