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Special Conditions Require Attention- Those with specific conditions such as eye problems, Lebers disease, kidney or liver disease, iron or folic acid deficiency, infections, or undergoing bone marrow-affecting treatments should seek professional advice

D., Van Landeghem, L., Sharek, L., Superfine, R., Garcia-Mata, R., et al

Pre-existing health conditions: Individuals with certain pre-existing health conditions, such as kidney or liver disease, should consult their healthcare provider before starting NAD+ supplementation to ensure it is safe and appropriate for their specific situation

Pregnant women who dont get enough folate intake put their babies at risk for brain and spinal cord defects