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Multiple commenters noted that hospitals receive routine market basket updates while Medicare PFS updates have been far below inflation, making this a structural problem that PE methodology changes alone cannot resolve

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Our primary hypothesis was that L-carnitine tartrate supplementation would improve recovery mainly by improving perceived muscle soreness and serum CK, an indicator of muscle damage

Safety considerations Researchers are monitoring for: Adverse events Potential safety signals Discontinuation rates Impacts on cardiovascular disease, heart failure, and sleep apnea Changes in blood pressure and HbA1c As with any emerging therapy, more data from Phase 3 trials will be needed to fully understand risk versus benefit

those with CV risk factors only, and in patients with and without prior MI or stroke