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Specifically, after removing 12 potentially influential observations, prefrontal GABA levels were significantly elevated in the persistent group compared to the control group ( = 0.149, P = 0.046)

[DOI] [PubMed] [Google Scholar] [67].Higashi T, Tateishi N, Sakamoto Y

found that repression of NRF2 antioxidant pathways served as a driver mechanism for the genetic premature aging disease Hutchinson-Gilford progeria syndrome (HGPS) [115], which is caused by constitutive progerin production, a mutant version of the nuclear protein lamin A