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Growth factors play a major role in initiating the angiogenesis process and several drugs act on these specific growth factors directly or indirectly which can be repurposed to activate angiogenesis and accelerate the healing of different types of wounds (burns, diabetic ulcers, and trauma wounds)

Keywords: diabetic peripheral neuropathy, diagnostic markers, pathogenesis, diabetes mellitus Introduction More than 50% of people with diabetes will develop diabetic neuropathy, which is one of the most common and troublesome complications of both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM)

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Direct interactions are related primarily to gut radiation and microbiota homeostasis, while indirect interactions are more related to other axes, like the MGBA