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[9] [10] If nausea becomes severe or persistent, patients should contact their healthcare provider, as dose adjustment may be necessary

Discomfort from constipation will usually last just as long as the constipation itself, often a few days, but potentially over multiple weeks

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The GLP-1 class includes drugs FDA-approved for type 2 diabetes (since exenatide in 2005) and for chronic weight management (liraglutide / Saxenda in 2014)

Because of this, many people regain weight after stopping semaglutide