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DNA-binding and in vitro cytotoxic activity of platinum(II) complexes of curcumin and caffeine

To inhibit PARPs, cells were pretreated with 10 M olaparib (Selleck, S1060) for 48 h prior to harvest

A lowered antioxidant status has been noted as one of the causes of depression, in addition to lower glutathione peroxidase activity (they play into each other)

21502-04) was as follows: 94 C for 5 min, 35 cycles of melting at 95 C for 30 s, annealing at 63 C for 30 s, and extension at 72 C for 10 s, with final extension at 72 C for 5 min in the end