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Discussion The vulnerability of dopaminergic neurons to minor perturbations in redox equilibrium is enhanced by the oxidative by-products of dopamine metabolism, resulting in their selective loss in Parkinsons disease

These B-series compounds (JWU B007 through B014) were obtained by modifying the annulation reaction so that the Lewis acid catalyst GaBr 3 was replaced with 20 mol% of TfOH (see Supplemental Material)