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Some practitioners extend titration even further for particularly sensitive individuals
K.JonesC
19 CaoS.ZhengM.HuaY.ChenG.KeepR
Moreover, oxidative stress makes the kidney tissue susceptible to damage by various alterations including the promotion of lipid peroxidation, protein modification, and DNA damage, leading to cell death [14]
Therapeutic approaches, such as antioxidant agents, ROS-scavenging enzymes, or targeted inhibition of NOX4-mediated ROS generation, may mitigate pathological remodeling and restore redox homeostasis, offering new methods to halt PF progression
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