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doi: 10.1093/jxb/erl164 105 ShumbeL.DAlessandroS.ShaoN.ChevalierA.KsasB.BockR.et al

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NAC treatment resulted in a decrease in all of these markers, ameliorated pulmonary dysfunction and prolonged lifespan in Bmi1 deficient mice ( 5 Conclusion In sum, metabolomic data presented herein support that senescent cells undergo changes in redox homeostasis, including a decrease in GSH synthesis, an increase in GSH degradation and reaction with oxidative species

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