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Reporting of Results: The final report must accurately reflect the data collected, providing a complete, clear, and truthful account of the study conducted

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The PDB structures with the following accession codes 2WCI, 3L4N, 3D4M, 3D5J, 2M80, 2WUL, 2WOU, 1MEK, 1B4Q and 4FIW were used in this work