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their functions include osmolyte, ion relocation, stomatal opening modulation, heavy metal detoxification, enzyme production and activity, gene expression, and redox homeostasis modulation [5]

The aim to improve the effect of metformin led to the development of phenformin 43 , which showed an improved cellular uptake compared to metformin 44

It binds to toxins, heavy metals, and other harmful substances, making them more water-soluble and facilitating their elimination through urine and bile