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The Nrf2KEAP1 pathway stands as a master regulator of this balance, transcriptionally activating genes involved in GSH biosynthesis (GCLC, GCLM, GSR, and GSS), iron metabolism (FTL, FTH1, FPN1, and HO-1), and redox defense (SLC7A11, GPX4, and NQO1)all of which directly modulate ferroptosis susceptibility (283, 284)
These intramuscular injections, usually containing cyanocobalamin or methylcobalamin, are administered weekly or monthly as prescribed by a healthcare provider
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Some people notice a decrease in inflammation and an improvement in their recovery times within the first couple of weeks