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76 Conditional knockout of GPX4 causes death of mouse embryonic fibroblasts in a lipid peroxide-dependent, non-apoptotic form and causes neurodegenerative disease in the cortical regions and hippocampus of the mouse brain

Dror, E

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These alterations in metabolic pathways, resulted in a significant decline in the levels of aspartate, uracil, serine, sarcosine, arginine, dehydroalanine, thymine, and porphobilinogen in LC patients versus HCs ( Figure 3B , Supplementary Figure 3A )

Nucleic Acids Research, 34 (90001), D668D672