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Can we achieve these goals pharmacologically

mBio 15, e0203223

GLP-1 medicines offer multi-faceted benefits: Reduce glucose and body weight Lower inflammation through weight loss and T cell activation Target multiple organs to reduce complications Show promise in treating cardio-renal issues and neurological disorders Exciting potential for broader applications

An individual participant data meta-analysis of 23 large randomised trials (covering over 150,000 people) found that during the first year of statin therapy, the absolute excess of muscle pain or weakness was about 11 cases per 1,000 people per year