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Keeping the plan on track Once a weekly cadence is set, sticking with it supports the consistency that adherence-sensitive effects depend on

Existing studies on weight loss and fertility often focus on lifestyle interventions or bariatric surgery, while pharmacologic approaches like GLP-1RAs remain understudied [21]

A possible explanation is that DPP-IV inhibition could not raise the GLP-1 levels sufficiently to therapeutic range when the basal GLP-1 level was too low to begin with (33)

By reducing insulin resistance through weight loss and direct metabolic effects, it decreases the demand placed on beta cells

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