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In the field of nanomedicine design, researchers have demonstrated the potential of multimodal therapy by loaded biomimetic nanoparticles (e.g., ZIF(Fe)&CB NPs) with iron ions and metabolic inhibitors, which synergistically enhance intracellular reactive oxygen species (ROS) accumulation in tumor cells and block aspartate metabolism compensation pathway(Zhang et al

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Reduced Allergol Immunopathol (Madr) 2019;47:365-71

Macimorelin provides a simple, orally available, well-tolerated, reproducible, and safe diagnostic test for AGHD, with accuracy comparable to that of the insulin tolerance test in adults (29)

This leptin-induced reduction in GABA action at POMC neurons is a disinhibition and is, in part, the mechanism by which leptin decreases feeding behaviors