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Published research has explored its role in promoting angiogenesis (new blood vessel formation), upregulating VEGF (vascular endothelial growth factor), stimulating fibroblast migration and collagen deposition, modulating nitric oxide pathways, and protecting the gastrointestinal lining

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Physicians usually prescribe B12 for fatigue, as the vitamin converts nutrients from food into glucose, which makes an individual experience a boosted energy level needed for intensive activities

Instead, it might help tolerate the medication better and boost energy production to reduce weakness and fatigue when taking a low-calorie diet with semaglutide