Subcutaneous injections of reserpine (1 mg/kg) resulted in a significant increase of MDA by 266.7% from 9.661 2.140 to 33.545 10.514 nM/g, H 2 O 2 by 30.6% from 0.023 0.011 to 0.116 0.023 mM/g, and NO by 12.3% from 9.323 1.582 to 27.117 6.909 M/g, while GSH decreased by 74% from 0.247 0.058 to 0.171 0.013 mM/g
Separate acute from chronic, and put a boundary on duration If someone is intent on using it, the least risky scenario is short-term use around a clearly defined acute injury window, not ongoing use for months for chronic pain
10.1113/jphysiol.2003.049478 152 TutemE.ApakR.BaykutF
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