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As is the case for humans(Ferrucci et al., 2005), we expected strong biological variation in senescence and the SASP in naturally aged wildtype mice
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This has led to ongoing investigation into its broader relationship with healthy ageing, cellular resilience and antioxidant defence systems
In murine models of acute liver failure, early-stage liver stem cells (LSCs) demonstrate superior hepatoprotective effects compared to mature hepatocytes
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