Why Vitamin B12 Matters for Nerve Health Vitamin B12 (cobalamin) is an essential water-soluble vitamin required for: Myelin repair (protective coating around nerves) Neurotransmitter function DNA synthesis & cellular repair Red blood cell formation & oxygen delivery The body cannot manufacture B12 , and deficiency is common especially among older adults, vegans/vegetarians, people with absorption disorders, and those taking drugs like metformin
Neuropathy due to vitamin B12 deficiency primarily affects the posterior columns of the spinal cord, and as it advances, can involve large-diameter myelinated fibers (A) in the peripheral nerves [12]
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