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Peptide bond hydrolysis by gastric proteases remains a real degradation risk

Vitamin B12 deficiency can lead to serious health issues like megaloblastic anemia, folate deficiency anemia, and nervous system damage

doi: 10.47895/amp.v50i2.2758 225

The measurement of TCN2-Cbl provides a more accurate reflection of the vitamin B12 status, particularly in the context of neurological disorders, as it specifically quantifies the fraction of Cbl bound to TCII and available for cellular uptake and metabolism [133]

Therefore, you might have symptoms such as weak muscles, numbness, trouble walking, nausea, weight loss, irritability, fatigue, and increased heart rate